I have never taken a product like this before and it really works. Feeling great and healthier. Love it!!
Product Overview
OnGuard goes beyond ordinary vitamins. Its heart is MycoFusion™, a patented complex that pairs shiitake with MaitakeGold 404™ — the maitake fraction Dr. Hiroaki Nanba spent years isolating and the University of Louisville confirmed is rich in “immune active” beta-glucans, granted U.S. Patent #5,854,404 because there is genuinely nothing like it. We layer that with colostrum, the antibody-rich first milk a mother cow makes only in the first days of her calf’s life, certified Grade A and collected solely from US dairies free of artificial hormones, antibiotics, and GMO.
Then we reach into traditions thousands of years old. Lo Han, the sweet Chinese melon Eastern healers have prized for centuries to support good health. And sacred lotus seed — the seed UCLA scientists found could still bloom after 1,288 years, supplying protective antioxidants studied for their role in healthy aging. The result is a far wider nutritional footprint than a single-ingredient pill, built for adults who want steady, everyday immune support. Shipped fresh from Sunrise, Florida by MDR, trusted for over 30 years by more than 2 million people.
What people say.
Thanks to MDR!!! Feeling better then ever since taking this wonderful formula!!
Onguard does me wonders, especially in the winter time. Having two homes where I eat off one of my property during harvest time and in the winter, I stay fit with my Onguard
The full story
Put Your Immune System OnGuard®

- If you don’t eat right
- Lack sufficient sleep
- Don’t have adequate levels of Vitamin A, D, or Zinc
- Suffer with certain chronic medical issues
- Are over 65 years of age
No matter how healthy you are, with advancing age your immune system declines. When you get rundown, older, or weakened by stress, latent viruses within you can resurface.
You Are Under Attack by Germs Daily!


Put the Odds in Your Favor Your good health relies on your body’s immune surveillance system. It must identify and remove dangerous invaders 24/7 to keep you in the best of health. MDR OnGuard unleashes powerful protective compounds into your body that can provide extraordinary immune support.
Shield Your Health with OnGuard®––Big Health Benefits from 2 Small Capsules! With all the challenges that plague us today, you need to support your immune system now more than ever. The OnGuard formula goes beyond vitamins with:
- MycoFusion: Proven, patented mushroom extract enhances immune cell activity and increases cell defenses.
- Colostrum: Transfers protective antibodies and immune factors derived from mother cow’s first milk for her calves.
- Lo Han Kuo: Chinese melon extract “Lo Han Kuo” prized for centuries to promote good health and longevity.
- Lotus Seeds: Longest living seeds (1,288 years) revitalize your health. Supplies protective nutrients and antioxidants.

MycoFusion™ Powers Up Your Immunity

Fortified with Colostrum Rich in Antibodies

Lo Han Melon Used For Centuries

Age-defying Lotus Seeds Boost Your Health!

MDR, a Name You Can Trust

Put Your Immune System OnGuard!
Frequently Asked Questions What’s the recommended use?
- Take one OnGuard capsule daily to support your immune system. Take one in the AM and one in the PM for peace of mind if you are run down or have immune challenges. The moment you suspect you are not feeling well, or have been exposed in public places, you may increase your dosage to 4 capsules per day (one every 6 hours).
Is OnGuard safe to take each day?
- Yes. It should be part of your preventive health supplementation regimen. The biggest advantage of OnGuard is that, unlike a popular herbal immune booster like Echinacea (a ragweed), OnGuard can be taken every day, for long periods – before, during, and after exposure to germs.
*All recommendations are subject to your health care provider’s approval as with any supplement. If I am on blood thinners, can I take OnGuard?
- You can take 1-2 capsules a day but do not exceed this dosage. Mushroom extracts may thin the blood, so although this supports healthy circulation for most people, for those taking blood thinners the added anti-coagulation effects must be considered and discussed with your physician.
*All recommendations are subject to your health care provider’s approval as with any supplement. If I am lactose intolerant can I take OnGuard?
- Most likely yes. OnGuard® contains Colostrum, a natural milk compound which does contain a very small amount of lactose. Most people who are lactose intolerant take OnGuard® with no difficulty. If you are ALLERGIC to milk or mushrooms do not take OnGuard®.
What’s the key to staying healthy?
- Supporting your immune system every day with a healthy diet, rest, frequent washing your hands, wearing a face mask in close public places and taking OnGuard® are the keys to staying healthy at this time.
What’s the Scientific Research?
- Read a study done by the NCBI (National Center for Biotechnology Information) about the Immune-enhancing effects of Maitake and Shiitake extracts. Click here to read.
- Read a study done by the NCBI (National Center for Biotechnology Information) about the effect of mushrooms. Click here to read.
- Read a study done by the NCBI (National Center for Biotechnology Information) about beta glucan. Click here to read.
What are the ingredients?
- Colostrum (from Grade A / U.S. Dairy Pasturized Milk)
- MycoFusion™ Mushroom Complex (MaitakeGold404 (Grifola Frondosa) and Shiitake (Lentinula Edodes) Brown Rice Biomass)
- Lo Han (Momordica Grosevonia) (Fruit)
- Sacred Lotus Seed Complex
- Gelatin
- Magnesium Stearate
- Silicon Dioxide
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Warnings & usage
- Do not exceed the recommended dose. Always follow the directions on the product label.
- If you are pregnant, nursing, taking medication, or managing a medical condition, consult your healthcare professional before use.
- Keep out of reach of children.
- Store in a cool, dry place away from direct sunlight. Do not use if the safety seal is broken or missing.
- Discontinue use and consult a healthcare professional if any adverse reaction occurs.
